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NAD+

Clinical evidence

Nicotinamide adenine dinucleotide is a coenzyme involved in energy metabolism and cellular repair. Not medical advice; consult a provider.

How NAD+ works

NAD+ levels decline with age; supplementation aims to support metabolism and repair pathways. Evidence is evolving; use under provider care.

Researched benefits

  • •Cellular energy and mitochondrial function
  • •Research in aging and longevity
  • •Support for sirtuins and DNA repair

What it is studied for

  • •Energy and fatigue in research
  • •Aging and cellular health
  • •Recovery and cognitive support in some protocols

Reported side effects and cautions

  • •Depends on form and route; flushing with niacin forms
  • •High-dose or IV use requires supervision

Dosing protocol described in the literature

Dosage
Varies by form
Frequency
As directed
Administration
IV, oral, or sublingual
Cycle
Varies

Cellular energy & longevity

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Evidence rating: Clinical evidence

Studied in human clinical trials. Some compounds in this tier are approved medicines for specific indications and require a prescription.

Other peptides

BPC157TB500 (Thymosin B4 Acetate)Semaglutide (Ozempic / Wegovy)Tirzepatide (GLP-1/GIP dual agonist)CagrilintideRetatrutide + Cagrilintide (combination)

See every peptide in the library →

Educational information only. This page is not medical advice, not a prescription, and not a recommendation to use NAD+. Dosing figures describe what appears in published research and provider protocols — they are not instructions. Several compounds covered here are prescription medicines. Talk to a licensed healthcare provider before acting on anything you read.